Phosphonoformate
Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium phosphonoformate). WebNov 1, 2024 · Foscarnet (pyrophosphate analog trisodium phosphonoformate) is the standard treatment of ganciclovir-resistant cytomegalovirus (CMV) infections or when …
Phosphonoformate
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WebDec 1, 2004 · Sodium phosphonoformate (PPF) is a pyrophosphate analogue that inhibits DNA polymerases and is used clinically for the treatment of cytomegalovirus (CMV) retinitis and refractory mucocutaneous... WebNov 22, 2024 · FosA proteins confer fosfomycin resistance to Gram-negative pathogens via glutathione-mediated modification of the antibiotic. In this study, we assessed whether inhibition of FosA by sodium phosphonoformate (PPF) (foscarnet), a clinically approved antiviral agent, would reverse fosfomycin resistance in representative Gram-negative …
http://www.cnreagent.com/s/sv243371.html Web中文别名: 二乙氧基膦酰基甲酸乙酯;甲膦酸三乙酯;膦甲酸三乙酯: 英文别名: Ethyl Diethoxyphosphinylformate(cas:1474-78-8);Diethoxyphosphinylformic Acid Ethyl Ester/(Ethoxycarbonyl)phosphonic Acid Diethyl Ester/Triethyl Phosphonoformate
WebTriethyl phosphonoformate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA CAS #: 1474-78-8 EC Number: 216-016-8 Molar Mass: 210.17 g/mol Hill Formula: C₇H₁₅O₅P 843410 View Pricing & Availability Recommended Products Overview Supporting Documentation Related Product … WebN4BP2L2 (NEDD4-binding protein 2-like 2), also known as PFAAP5 (phosphonoformate immuno-associated protein 5), is a 583 amino acid nuclear protein that potentially is involved in transcriptional regulation. N4BP2L2 is phosphorylated on Ser 199 in response to DNA damage, probably by ATM or ATR. Primarily expressed in bone marrow, N4BP2L2 is ...
WebSodium phosphonoformate tribasic hexahydrate Synonym (s): Foscarnet, Phosphonoformic acid trisodium salt hexahydrate Linear Formula: Na2O3PCO2Na · 6H2O CAS No.: 34156 …
WebJan 1, 2001 · Abstract. Phosphonoformate inhibited the replication of Herpes simplex virus (HSV) type 1 and type 2 in culture. The concentration required to inhibit the replication of … flow simulator onlineWebAbstract. This article describes the antiviral properties of foscarnet (trisodium phosphonoformate) at the enzyme level as well as in cell cultures and in vivo. The … flows inWebFoscarnet (Foscavir), or phosphonoformic acid (PFA), is an inorganic pyrophosphate analogue that inhibits all known human herpesviruses, including most ganciclovir-resistant CMV isolates and acyclovir-resistant HSV and VZV strains (see Table 295.4 ). 284 Foscarnet also is active against HIV. green colored fire extinguishersWebNov 22, 2024 · In this study, we assessed whether inhibition of FosA by sodium phosphonoformate (PPF) (foscarnet), a clinically approved antiviral agent, would reverse … flows in frenchWebJun 1, 2000 · Monoalkyl ether lipid analogues of foscarnet (phosphonoformate, PFA) exhibit substantially greater in vitro antiviral activity than unmodified PFA against human immunodeficiency virus type 1 (HIV-1). Our previous studies indicate that the length of the alkyl chain must be 14–22 carbons for optimal antiviral activity. flow sin gastar datosWebDec 1, 1998 · Foscarnet (trisodium phosphonoformate)is an antiviral agent that has activity against herpesviruses,including cytomegalovirus (CMV),Epstein-Barr virus, herpes simplex virus (HSV) types 1 and 2, and varicella zoster virus (VZV). It also has activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV). green colored eyeshadowWebThese are: phosphite of acycloguanosine (P-ACG), Ara-A, cidofovir (CDV), ribavirin (Rib), phosphonoformate (PFA), glycyrrhizic acid (GLN) and alpha-interferon (alpha-IFN). All studied double combinations and triple combinations including P-ACV inhibited replication of both HSV strains more effectively than any drug alone. green colored eyes